"Following the game against Pittsburgh, where Devonta injured his foot, we thought he was just having general soreness in his groin area," Quinn said. "As the week went on, it continued, so we decided to have him get some tests. It has been determined that he will need a procedure that will result in us placing him on injured reserve.
"We are hopeful he will be able to return this season, but we will have a better feel for that in the coming weeks."
A source told ESPN that Freeman is scheduled to have the procedure Thursday in Philadelphia.
Freeman played in just two of the first six games while slowed by knee, foot and groin injuries. He injured his right knee in a season-opening loss at Philadelphia and missed three games. Then in a Week 5 loss at Pittsburgh, Freeman suffered the foot and groin injuries.
With Freeman out, the Falcons now will return to Tevin Coleman as the starter with rookie Ito Smith as the backup. Coleman is averaging 3.7 rushing yards per game, while Smith set a franchise rookie record this past weekend by scoring a rushing touchdown in his third consecutive game.
The Falcons signed Freeman to a five-year, $41.25 million extension last year that included $22 million in guaranteed money. Coleman, meanwhile, is in the last year of his rookie contract.
Freeman, 26, rushed for 865 yards and 7 touchdowns on 196 carries in 2017. He had back-to-back 1,000-rushing-yard seasons in 2015 and '16. Last year, a significant right knee injury limited Freeman's production.
The Falcons are allowed to bring two players back from IR. Freeman wouldn't be able to return to practice until six weeks from Tuesday, and he can't play in a game until the Falcons face the Panthers on Dec. 23. His return likely wouldn't happen, however, if the Falcons aren't in the playoff picture.
His move to IR is just the latest in a string of injury woes for the Falcons. They lost Pro Bowl strong safety Keanu Neal to a season-ending ACL tear, while Pro Bowl middle linebacker Deion Jones currently is on IR while recovering from foot surgery.
Jones could return from IR by the Nov. 18 game against Dallas, if healthy.
Falcons veteran kicker Matt Bryant suffered a hamstring strain after making a 57-yard field goal against the Bucs on Sunday. The team on Tuesday signed Giorgio Tavecchio to handle the kicking duties for at least Monday night's home game against the New York Giants.