| Pitching | |||||||||||||
| RK | PITCHER | DATE | OPP | SCORE | IP | H | R | ER | BB | SO | PIT | DEC | GSC |
| 1 | Sandy Alcantara, MIA | 4/1 | CHW | W 10-0 | 9.0 | 3 | 0 | 0 | 0 | 7 | 93 | W | 88 |
| 2 | Ranger Suarez, BOS | 4/27 | @ TOR | W 5-0 | 8.0 | 1 | 0 | 0 | 1 | 10 | 105 | W | 89 |
| Tyler Glasnow, LAD | 4/23 | @ SF | W 3-0 | 8.0 | 1 | 0 | 0 | 1 | 9 | 105 | W | 88 | |
| Max Fried, NYY | 4/22 | @ BOS | W 4-1 | 8.0 | 3 | 0 | 0 | 2 | 9 | 100 | W | 83 | |
| Jose Soriano, LAA | 4/6 | ATL | W 6-2 | 8.0 | 3 | 1 | 1 | 0 | 10 | 97 | W | 82 | |
| Ranger Suarez, BOS | 4/17 | DET | W 1-0 | 8.0 | 2 | 0 | 0 | 1 | 4 | 93 | ND | 81 | |
| Michael Wacha, KC | 4/11 | CHW | W 2-0 | 8.0 | 4 | 0 | 0 | 1 | 7 | 88 | W | 80 | |
| Justin Wrobleski, LAD | 4/13 | NYM | W 4-0 | 8.0 | 2 | 0 | 0 | 0 | 2 | 90 | W | 80 | |
| Parker Messick, CLE | 4/16 | BAL | W 4-2 | 8.0 | 2 | 2 | 2 | 2 | 9 | 112 | W | 77 | |
| 10 | Gavin Williams, CLE | 4/29 | TB | W 3-1 | 7.2 | 5 | 1 | 0 | 0 | 9 | 95 | W | 76 |
| 11 | Ryan Weathers, NYY | 4/19 | KC | W 7-0 | 7.1 | 5 | 0 | 0 | 1 | 8 | 95 | W | 75 |
| 12 | Kris Bubic, KC | 4/10 | CHW | W 2-0 | 7.0 | 2 | 0 | 0 | 1 | 11 | 88 | W | 83 |
| Paul Skenes, PIT | 4/24 | @ MIL | W 6-0 | 7.0 | 1 | 0 | 0 | 0 | 7 | 93 | W | 82 | |
| Jesus Luzardo, PHI | 4/28 | SF | W 7-0 | 7.0 | 2 | 0 | 0 | 0 | 8 | 88 | W | 81 | |
| Jose Soriano, LAA | 4/12 | @ CIN | W 9-6 | 7.0 | 2 | 0 | 0 | 3 | 10 | 106 | W | 80 | |
| Gavin Williams, CLE | 4/1 | @ LAD | W 4-1 | 7.0 | 2 | 0 | 0 | 3 | 10 | 85 | W | 80 | |
| Bryan Woo, SEA | 4/3 | @ LAA | W 3-1 | 7.0 | 1 | 0 | 0 | 1 | 6 | 87 | ND | 80 | |
| Foster Griffin, WSH | 4/26 | @ CHW | W 2-1 | 7.0 | 2 | 0 | 0 | 2 | 8 | 95 | ND | 79 | |
| Jeffrey Springs, ATH | 4/9 | @ NYY | W 1-0 | 7.0 | 1 | 0 | 0 | 2 | 6 | 93 | W | 79 | |
| Mick Abel, MIN | 4/14 | BOS | W 6-0 | 7.0 | 4 | 0 | 0 | 0 | 10 | 90 | W | 79 | |
| Seth Lugo, KC | 4/20 | BAL | L 5-7 | 7.0 | 1 | 0 | 0 | 4 | 7 | 93 | ND | 78 | |
| Gavin Williams, CLE | 4/18 | BAL | W 4-2 | 7.0 | 3 | 1 | 1 | 1 | 11 | 100 | W | 77 | |
| Nathan Eovaldi, TEX | 4/13 | @ ATH | W 8-1 | 7.0 | 3 | 0 | 0 | 2 | 7 | 84 | W | 76 | |
| Max Fried, NYY | 3/31 | @ SEA | W 5-0 | 7.0 | 3 | 0 | 0 | 1 | 6 | 90 | W | 76 | |
| Randy Vasquez, SD | 4/21 | @ COL | W 1-0 | 7.0 | 3 | 0 | 0 | 0 | 5 | 84 | W | 76 | |
| Nathan Eovaldi, TEX | 4/29 | NYY | W 3-0 | 7.0 | 4 | 0 | 0 | 1 | 7 | 102 | W | 75 | |
| Nolan McLean, NYM | 4/14 | @ LAD | L 1-2 | 7.0 | 2 | 1 | 1 | 2 | 8 | 95 | ND | 75 | |
| Tyler Glasnow, LAD | 4/17 | @ COL | W 7-1 | 7.0 | 2 | 1 | 1 | 2 | 7 | 92 | W | 74 | |
| Nick Martinez, TB | 4/28 | @ CLE | W 1-0 | 7.0 | 3 | 0 | 0 | 1 | 4 | 78 | W | 74 | |
| 30 | Cam Schlittler, NYY | 4/1 | @ SEA | W 5-3 | 6.1 | 2 | 0 | 0 | 0 | 7 | 79 | W | 76 |
| 31 | Kyle Harrison, MIL | 4/26 | PIT | W 5-0 | 6.0 | 1 | 0 | 0 | 1 | 12 | 101 | W | 81 |
| Emerson Hancock, SEA | 3/29 | CLE | W 8-0 | 6.0 | 0 | 0 | 0 | 1 | 9 | 97 | W | 80 | |
| Shota Imanaga, CHC | 4/10 | PIT | L 0-2 | 6.0 | 0 | 0 | 0 | 1 | 9 | 100 | ND | 80 | |
| Kevin Gausman, TOR | 4/1 | COL | L 1-2 | 6.0 | 2 | 0 | 0 | 0 | 10 | 89 | ND | 78 | |
| Chris Sale, ATL | 4/26 | PHI | W 6-2 | 6.0 | 1 | 0 | 0 | 2 | 9 | 100 | W | 77 | |
| Kevin Gausman, TOR | 3/27 | ATH | W 3-2 | 6.0 | 1 | 1 | 1 | 0 | 11 | 83 | ND | 77 | |
| Drew Rasmussen, TB | 4/12 | NYY | W 5-4 | 6.0 | 1 | 0 | 0 | 0 | 7 | 76 | W | 77 | |
| Cristopher Sanchez, PHI | 3/26 | TEX | W 5-3 | 6.0 | 3 | 0 | 0 | 0 | 10 | 87 | W | 76 | |
| Slade Cecconi, CLE | 4/5 | CHC | L 0-1 | 6.0 | 1 | 0 | 0 | 1 | 6 | 85 | ND | 75 | |
| Michael McGreevy, STL | 3/28 | TB | W 6-5 | 6.0 | 0 | 0 | 0 | 2 | 5 | 96 | ND | 75 | |