Napoli put on a dazzling display to mark the first anniversary of Diego Maradona's death when they stormed to a 4-0 win over Lazio on Sunday.
AC Milan slipped to their second successive Serie A defeat when Sassuolo stunned their opponents in the San Siro with a 3-1 comeback win.
Hakan Calhanoglu thrashed home a powerful first-half strike and Lautaro Martinez converted a penaltyfor Inter Milan to beat Venezia 2-0.
Juventus suffered another setback as they lost 1-0 at home to Atalanta after a Duvan Zapata goal on Saturday, with a fifth defeat in 14 games.
Finance police have searched the offices of Juventus in Turin and Milan, seeking documents relating to transfers between 2019 and 2021.
Napoli striker Victor Osimhen will be out of action for the next three months due to a facial injury, and will miss the Africa Cup of Nations.
Victor Osimhen's immense Serie A progress hit an unexpected roadblock against Inter, while Felix Afena-Gyan enjoyed a weekend he will never forget.
Ghanaian teenage substitute Felix Afena-Gyan's first senior goals earned Jose Mourinho's AS Roma a 2-0 victory at Genoa in Serie A on Sunday.
Inter Milan ended Napoli's unbeaten start to the Serie A season after coming from behind to earn a thrilling 3-2 victory at the San Siro on Sunday.
Fiorentina inflicted a first Serie A defeat of the season on AC Milan with a 4-3 victory in Florence on Saturday.
Juventus defender Leonardo Bonucci scored a penalty in each half to earn his side a 2-0 win over Lazio on Saturday.
With the international break over, attention turns back to club football. Here are the best images from the first three months of 2021-22 in Europe.
With a third of the season gone and the January transfer window ahead, we pick out players who'd fix what's broken at Europe's biggest sides.
Who will be crowned champions of ESPN's Battle of the Leagues, presented by EA Sports FIFA 22? Will Ligue 1 or the Premier League reign supreme?
We're into the semifinals of ESPN's Battle of the Leagues, presented by EA Sports FIFA 22. Will Ligue 1 beat Serie A? Bundesliga or Premier League?
Napoli paid tribute to a club legend on Sunday by wearing a special kit designed in honour of the late Argentina great Diego Maradona.
Xavi Hernandez saw the size of his task, Ole Gunnar Solskjaer had another setback and Max Allegri has not restored the glory days. What a weekend!
AC Milan continued their unbeaten start to the Serie A season with a 1-1 draw against Inter Milan in an enthralling Milan Derby on Sunday.
Napoli dropped points for the second time this season in Serie A with a 1-1 draw at home to Hellas Verona on Sunday.
Lazio have hit out at the makers of the dramatised "Maradona: Blessed Dream" series for a scene in which the Roman club are branded fascists.
Genoa have appointed former Ukraine coach Andriy Shevchenko as their manager on a deal until 2024, the Serie A club announced on Sunday.
Roma's slump continued with a 3-2 Serie A defeat by relegation battling Venezia on Sunday.
Juan Cuadrado's stoppage-time strike earned Juventus a 1-0 win over 10-man Fiorentina as the Turin club ended a three-match winless league run.